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Zolpidem Tartrate

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(Treatment for insomnia)

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Zolpidem is in a class of drugs called sedative/ hypnotics or sleep medications. Zolpidem is used to treat sleep disorders such as trouble falling asleep , waking up many times during the night, or waking up too early in the morning. Zolpidem is for short-term use only--usually 7 to 10 days.

Zolpidem Tartrate is manufactured by "Sanofi-Synthelabo"

Trade Mark: Ambien

Description

Zolpidem tartrate, is a non-benzodiazepine hypnotic of the imidazopyridine class and is available in 5-mg and 10-mg strength tablets for oral administration.

Zolpidem: N,N,6-trimethyl-2-p-tolylimidazo[1,2-a] pyridine-3-acetamide L-(+)-tartrate (2:1).

CAS: 99294-93-6

Structure as following:

Zolpidem tartrate is a white to off-white crystalline powder that is sparingly soluble in water, alcohol, and propylene glycol.

It has a molecular weight of 764.88.

Each Ambien tablet includes the following inactive ingredients: hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide; the 5-mg tablet also contains FD&C Red No. 40, iron oxide colorant, and polysorbate 80.

Zolpidem tartrate is indicated for the short-term treatment of insomnia. Zolpidem has been shown to decrease sleep latency and increase the duration of sleep for up to 35 days in controlled clinical studies

Dosage of the drug.

The dose of Ambien should be individualized.

The recommended dose for adults is 10 mg immediately before bedtime.

Side Effects:

Most common side effects: All medicines have side effects. Most common side effects of sleep medicines include:

You may find that these medicines make you sleepy during the day. How drowsy you feel depends upon how your body reacts to the medicine, which sleep medicine you are taking, and how large a dose your doctor has prescribed. Daytime drowsiness is best avoided by taking the lowest dose possible that will still help you sleep at night. Your doctor will work with you to find the dose of Zolpidem that is best for you.

Waht ohter drugs will affect zolpidem?

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