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Latanoprost

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(CAS: 130209-82-4)

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CAS: 130209-82-4

Chemical Name: isopropyl - (Z)- 7 [(1R,2R,3R,5S) 3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoate.

Molecular Formula: C26H40O5

Structure:


Latanoprost is a colorless to slightly yellow oil that is very soluble in acetonitrile and freely soluble in acetone, ethanol, ethyl acetate, isopropanol, methanol and octanol. It is practically insoluble in water.

What is the most important information I should know about latanoprost ophthalmic?

#Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye possibly resulting in a loss of vision.
#Latanoprost ophthalmic may cause the iris (the colored part of the eye) to change. The amount of brown pigment in the eyes may increase during treatment with latanoprost ophthalmic. This effect occurs primarily in people with blue or green eyes. It is not known if color changes are reversible after therapy is stopped. Color changes may occur only in the eye being treated.
#Latanoprost ophthalmic contains a preservative (benzalkonium chloride), so do not wear soft contact lenses when applying this medication. Contact lenses can be inserted 15 minutes after application of the drops.

What is latanoprost ophthalmic?

# Latanoprost ophthalmic reduces pressure in the eye by increasing the amount of fluid that drains from the eye.
#Latanoprost ophthalmic is used to treat glaucoma and high pressure in the eye(s).
#Latanoprost ophthalmic may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using latanoprost ophthalmic?

#Before using this medication, tell your doctor about your medical history. If you have any other medical conditions, you may require special monitoring during treatment with latanoprost ophthalmic.
#Latanoprost ophthalmic is in the FDA pregnancy category C. This means that it is not known whether latanoprost ophthalmic will be harmful to an unborn baby. Do not use latanoprost ophthalmic without first talking to your doctor if you are pregnant or could become pregnant during treatment.
#It is not known whether latanoprost passes into breast milk. Do not use latanoprost ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use latanoprost ophthalmic?

# Use latanoprost ophthalmic eyedrops exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, pharmacist, or nurse to explain them to you.
#Latanoprost ophthalmic is usually used once a day, one drop in the affected eye or eyes, in the evening. Since latanoprost ophthalmic is used regularly, try to make applying them a part of your nightly routine. Follow your doctor's instructions.
#Wash your hands before and after using the eyedrops.
#Latanoprost ophthalmic contains a preservative (benzalkonium chloride), so do not wear soft contact lenses when applying this medication. Contact lenses can be inserted 15 minutes after application of the drops.
# To apply the eyedrops:
, Tilt the head back slightly and pull down on your lower eyelid. Position the dropper above the eye. Steady the hand holding the bottle by placing your thumb against your brow or the bridge of your nose. Look up and away from the dropper. Gently press or lightly tap the side of the bottle to allow only a single drop of medicine to fall into the pocket formed by the lower eyelid. Do not allow the dropper to touch the eye, eyelid, or hands. Instill the number of drops prescribed by your doctor. Close your eye for approximately 2 to 3 minutes. If you are using drops in both eyes, repeat this procedure in the other eye.
#Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye possibly resulting in a loss of vision.
#Contact your doctor if you if you experience any type of eye condition or if you need to have eye surgery.
#Do not use any eyedrop that is discolored or has particles in it.
# If you are also using another type of eye medication, apply it at least 5 minutes before or after a dose of latanoprost ophthalmic, unless otherwise directed by your doctor.
# Store latanoprost ophthalmic in the refrigerator before the bottle is opened.
# Once the bottle is opened, latanoprost ophthalmic can be stored at room temperature up to 77 degrees Fahrenheit for 6 weeks. Keep the bottle properly capped.

What happens if I miss a dose?

# Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose?

#If an overdose is suspected, flush the eye with water and seek emergency medical attention.
#Symptoms of a latanoprost ophthalmic overdose may include burning, irritation, and redness of the eyes.

What should I avoid while using latanoprost ophthalmic?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.
#Latanoprost ophthalmic contains a preservative (benzalkonium chloride), so do not wear soft contact lenses when applying this medication. Contact lenses can be inserted 15 minutes after application of the drops.
#If you are also using another type of eye medication, apply it at least 5 minutes before or after a dose of latanoprost ophthalmic, unless otherwise directed by your doctor.

What are the possible side effects of latanoprost ophthalmic?

# Call your doctor immediately if you notice signs of infection such as itching, redness, or discharge from the eyes.
# More commonly, burning, stinging, itching, redness, blurred vision, dry eye, tearing, eyelid irritation, or a feeling of something in your eye may occur. Continue to use latanoprost ophthalmic and talk to your doctor about these side effects.
# Latanoprost ophthalmic may cause the iris (the colored part of the eye) to change. The amount of brown pigment in the eyes may increase during treatment with latanoprost ophthalmic. This effect occurs primarily in people with blue or green eyes. It is not known if color changes are reversible after therapy is stopped. Color changes may occur only in the eye being treated.
# Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect latanoprost ophthalmic?
# Before using this medication, tell your doctor if you are using another eye medication. Apply other eyedrops at least 5 minutes before or after a dose of latanoprost ophthalmic to prevent an interactions.
# Drugs other than those listed here may also interact with latanoprost ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?
# Your pharmacist has additional information about latanoprost ophthalmic written for health professionals that you may read.