CAS No.: 9067-32-7
According to the different application purpose, sodium hyaluronate can be classfied into cometic grade, eye drop grade, injection grade and food grade.
Hyaluronic Acid (HA) is a mucopolysaccharide composed of repeat disaccharide units of N-acetylglucosamine and glucuronic acid. The commercial HA is commonly a sodium salt, called sodium hyaluronate. HA is widely found in the extracellular matrix of animal tissues and vitreous humor. Its main biological role is water retention and lubrication.
Water retention and anti-wrinkle: The skin moisturize level is closely related to HA content in the dermis. As one¡¯s age increases, HA content in skin decreases. As a result the water retaining ability of the skin is weakened and the skin looks wrinkled. HA solution has high viscoelasticity and lubricity. When it is applied to the skin and hair, it can form an air permeable layer and keep the skin moist and smooth. Low molecular weight HA can penetrate into dermis, promote skin blood microcirculation and nutrient absorption. So HA plays a role of wrinkle removing, look improving and health protecting. HA restores elasticity and hydration to skin and gives it a more youthful appearance.
Sun-screen action: HA can eliminate active oxygen free radical produced by ultraviolet radiation in the epidermis, and protect skin from being damaged.
Repair and prevention action: HA can promote regeneration of injured skin by accelerating proliferation and differentiation of the epidermal cells.
HA is one of the best natural moisturizing components used in cosmetics and is recommended in all kinds of skin-care, hair-care products. The supplement is about 0.05~0.5%.
What is sodium hyaluronate?
Sodium hyaluronate is similar to synovial fluid, a substance that occurs naturally in the joints. Synovial fluid acts as a lubricant and shock absorber.
Sodium hyaluronate is injected into the knee joints for the treatment of pain in individuals with osteoarthritis.
Sodium hyaluronate may also be used for purposes other than those listed here.
How should I use sodium hyaluronate?
Sodium hyaluronate is administered by a healthcare professional as an intra-articular (into the joint) injection.
Temporary pain or swelling of the affected joint may occur after injection of sodium hyaluronate.
Avoid strenuous activity or prolonged (longer than one hour) weight-bearing activity such as jogging, tennis, or lifting weights for 48 hours following an injection, unless otherwise directed by your doctor.
What are the possible side effects of sodium hyaluronate?
Notify your doctor immediately if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to sodium hyaluronate.
Other less serious side effects may also occur. Talk to your doctor if you experience
- Temporary pain or swelling of the affected joint;
- Rash or bruising at the injection site;
- Headache; or
- Upset stomach.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.