Chemical Name: butyl (R)-2-[4-(4-cyano-2-fluorophenoxy) phenoxy] propionate
Description: the material shall consist of cyhalofop-butyl with related manufacturing impurities and shall be an off-white granular solid.
Identity test: identity of the active constituent must be established by spectroscopic tests (IR spectrum, NMR, mass spectra), Chromatography (HPLC or GC retention time with reference compound) or any other suitable test method.
Composition: the material is the resolved (R)-isomer
6.1 Active constituent: 950 g/kg minimum
July 2005 - Evaluation of the new active Cyhalofop-Butyl in the product Barnstorm Herbicide. Australian Pesticides and Veterinary Medicines Authority (APVMA). Canberra, Australia. Barnstorm herbicide is proposed to be used for the post emergence control of barnyar grasses and silver top grass in rice. Cyhalofop-butyl is manufactured in Japan. Barnstorm Herbicide will be formulated in New Zealand and transported to Australia fully packed. The label recommends both ground and aerial applications. Almost all applications (~95%) are expected to be aerially applied with just ~5 % applied by groundrigs.
February 16, 2001 - Summary of Toxicological data (Cyhalofop-Butyl). California Environmental Protection Agency. Department of Pesticide Regulation. Medical Toxicology Branch.
September 18, 2002: European Commission Health & Consumer Protection Directorate-General. Review report for the active substance cyhalofop-butyl. Finalised in the Standing Committee on the Food Chain and Animal Health at its meeting on 19 April 2002 in view of the inclusion of cyhalofop-butyl in Annex I of Directive 91/414/EEC.
February 18, 2002 - European Commission decision to extend provisional authorisation for new active substances including cyhalofop-buty
Glossary of Pesticide Chemicals, October 2001. A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration. Also available at: http://vm.cfsan.fda.gov/~acrobat/pestglos.pdf
August, 2001 - IR-4: New Products/Transitional Solution List - This list contains brief descriptions of numerous new pest control materials that have been introduced over the last several years. Additionally, it contains information on some "older" crop protection chemicals that are believed to have room for new uses. This List includes Cyhalofop-butyl.
- The analytical method used for the determination of the active constituent and toxicological significant impurities must be validated in accordance with the APVMA guidelines for the validation of analytical methods.
- Collaboratively tested standard CIPAC and AOAC methods for the analysis for the active constituent and any method submitted as a part of the new active constituent application that has been accepted by the APVMA are regarded as validated and do not require revalidation.
- Unless the scope of the collaborative method (CIPAC and AOAC) also includes toxicological significant impurities in the active constituent, validation data for impurities are required.
- Validation data for related impurities are not be required.